B.Pharmacy 4th Semester Pharmacology-1 Notes

Pharmacology–I notes for B.Pharmacy 4th semester cover basic principles of pharmacology, pharmacokinetics, pharmacodynamics, and drugs acting on the autonomic nervous, cardiovascular, and gastrointestinal systems. These notes help students understand mechanisms of action, therapeutic uses, adverse effects, and clinical applications, forming a strong foundation for rational drug therapy and advanced pharmacology studies.

Bachelor of Pharmacy
Semester		4th Semester		Subject		Pharmacology
Syllabus
Unit 1st	General Pharmacology a. Introduction to Pharmacology- Definition, historical landmarks and scope of pharmacology, nature and source of drugs, essential drugs concept and routes of drug administration, agonists, antagonists (competitive and non-competitive), spare receptors, addiction, tolerance, dependence, tachyphylaxis, idiosyncrasy, and allergy. b. Pharmacokinetics – Membrane transport, absorption, distribution, metabolism and excretion of drugs. Enzyme induction, enzyme inhibition, kinetics of elimination
Click Here
Unit 2nd	General Pharmacology a. Pharmacodynamics – Principles and mechanisms of drug action. Receptor theories and classification of receptors, regulation of receptors. drug receptor interactions, signal transduction mechanisms, G-protein–coupled receptors, ion channel receptors, transmembrane enzyme-linked receptors, transmembrane JAK-STAT binding receptor and receptors that regulate transcription factors, dose-response relationship, therapeutic index, combined effects of drugs and factors modifying drug action. b. Adverse drug reactions. c. Drug interactions (pharmacokinetic and pharmacodynamic) d. Drug discovery and clinical evaluation of new drugs – drug discovery phase, preclinical evaluation phase, clinical trial phase, phases of clinical trials and pharmacovigilance
Click Here
Unit 3rd	Pharmacology of drugs acting on peripheral nervous system a. Organization and function of ANS. b.Neurohumoral transmission,co-transmission and classification of neurotransmitters. c. Parasympathomimetics, Parasympatholytics, Sympathomimetics, sympatholytics. d. Neuromuscular blocking agents and skeletal muscle relaxants (peripheral). e. Local anesthetic agents. f. Drugs used in myasthenia gravis and glaucoma
Click Here
Unit 4th	Pharmacology of drugs acting on central nervous system a. Neurohumoral transmission in the C.N.S., with special emphasis on the importance of various neurotransmitters like GABA, glutamate, glycine, serotonin, and dopamine. b. General anaesthetics and pre-anaesthetics. c. Sedatives, hypnotics and centrally acting muscle relaxants. d. Anti-epileptics e. Alcohols and disulfiram
Click Here
Unit 5th	Pharmacology of drugs acting on central nervous system a. Psychopharmacological agents: Antipsychotics, antidepressants, anti-anxiety agents, anti-manics and hallucinogens. b. Drugs used in Parkinson’s disease and Alzheimer’s disease. c. CNS stimulants and nootropics. d. Opioid analgesics and antagonists e. Drug addiction, drug abuse, tolerance and dependence.
Click Here

Pharmacology–I introduces the basic principles of pharmacology, including routes of drug administration, pharmacokinetics, and pharmacodynamics. It covers drugs acting on the autonomic nervous system, cardiovascular system, and gastrointestinal tract. The subject emphasizes mechanisms of action, therapeutic uses, adverse effects, contraindications, and clinical relevance, providing a strong foundation for rational drug therapy and advanced pharmacological studies.

• First of all visit the website carewellpharma.shop
• After that select semester in B.Pharma
• And then select the subject
• After that you will get the download button, save it from there.

Home