B Pharmacy 7th Semester Novel Drug Delivery System Notes

B.Pharmacy 7th Semester Novel Drug Delivery System notes covering controlled and targeted drug delivery, polymers, microencapsulation, transdermal, gastroretentive, nasopulmonary, ocular and intrauterine systems. Exam-oriented, well-structured notes for clear concepts and university exam preparation.

Novel Drug Delivery System Notes

Novel Drug Delivery System Overview

Bachelor of Pharmacy
Semester7th SemesterSubjectNovel Drug Delivery System
Syllabus
Unit 1stControlled drug delivery systems: Introduction, terminology/definitions and rationale, advantages, disadvantages, selection of drug candidates.Approaches to design controlled release formulations based on diffusion, dissolution and ion exchange principles.
Physicochemical and biological properties of drugs relevant to controlled release formulations
Polymers: Introduction, classification, properties, advantages and application of polymers in formulation of controlled release drug delivery systems.
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Unit 2ndMicroencapsulation: Definition, advantages and disadvantages, microspheres/microcapsules, microparticles, methods of microencapsulation, applications
Mucosal Drug Delivery system: Introduction, Principles of bioadhesion / mucoadhesion, concepts, advantages and disadvantages, transmucosal permeability and formulation considerations of buccal delivery systems
Implantable Drug Delivery Systems: Introduction, advantages and disadvantages, concept of implantsand osmotic pump
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Unit 3rdTransdermal Drug Delivery Systems: Introduction, Permeation through skin, factors affecting permeation, permeation enhancers, basic components of TDDS, formulation approaches
Gastroretentive drug delivery systems: Introduction, advantages, disadvantages, approaches for GRDDS– Floating, high density systems, inflatable and gastro-adhesive systems and their applications
Nasopulmonary drug delivery system: Introduction to Nasal and Pulmonary routes of drug delivery, Formulation of Inhalers (dry powder and metered dose), nasal sprays, nebulizers
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Unit 4thTargeted drug Delivery: Concepts and approaches advantages and disadvantages, introduction to liposomes, niosomes, nanoparticles, monoclonal antibodies and their applications
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Unit 5thOcular Drug Delivery Systems: Introduction, intra ocular barriers and methods to overcome – preliminary study, ocular formulations and ocuserts
Intrauterine Drug Delivery Systems: Introduction, advantages and disadvantages, development of intra uterine devices (IUDs) and applications
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Unit Summary

Unit-I to Unit-V of the Novel Drug Delivery System course covers advanced drug delivery concepts aimed at improving therapeutic efficacy and patient compliance. Topics include controlled release systems, polymers, microencapsulation, mucosal and implantable delivery, transdermal and gastroretentive systems, nasopulmonary delivery, targeted drug delivery using liposomes and nanoparticles, and specialized systems like ocular and intrauterine drug delivery. The syllabus is concept-oriented, application-focused, and designed for strong exam preparation and practical understanding.

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