Unit 3 of Medicinal Chemistry–II for B.Pharmacy 5th semester covers anti-arrhythmic drugs, anti-hyperlipidaemic agents, coagulants, anticoagulants, and drugs used in congestive heart failure. The notes explain chemical structures, mechanisms of action, SAR, synthesis, and therapeutic uses of cardiovascular and blood-related drugs, providing pharmacy students with essential knowledge for rational drug design, clinical applications, and exam preparation.
Medicinal Chemistry Unit 3 Overview
| Bachelor of Pharmacy | |||||||
| Semester | 5th Semester | Subject | Medicinal Chemistry II | ||||
| Syllabus | |||||||
| Unit 3rd | Anti-arrhythmic Drugs: Quinidine sulphate, Procainamide hydrochloride, Disopyramide phosphate, Phenytoin sodium, Lidocaine hydrochloride, Tocainide hydrochloride, Mexiletine hydrochloride, Lorcainide hydrochloride, Amiodarone,Sotalol. Anti-hyperlipidaemic agents: Clofibrate, Lovastatin, Cholesteramine and Cholestipol Coagulants & Anticoagulants: Menadione, Acetomenadione, Warfarin, Anisindione,clopidogrel Drugs used in Congestive Heart Failure: Digoxin, Digitoxin, Nesiritide, Bosentan,Tezosentan. | ||||||
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Unit Summary
Unit 3 focuses on cardiovascular and blood-related drugs. It covers anti-arrhythmic agents (Quinidine, Procainamide, Lidocaine, Amiodarone, Sotalol), anti-hyperlipidaemic drugs (Clofibrate, Lovastatin, Cholestyramine, Cholestipol), coagulants and anticoagulants (Vitamin K analogues, Warfarin, Clopidogrel), and drugs for congestive heart failure (Digoxin, Digitoxin, Nesiritide, Bosentan, Tezosentan). Emphasis is on chemical structures, mechanisms of action, SAR, and therapeutic applications for effective pharmacy practice.
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