B.Pharm 1st Semester Pharmaceutics -I syllabus explained with unit-wise theory and practical details. Covers dosage forms, calculations, prescriptions, and pharmaceutical incompatibilities
Unit 1
Historical background and development of profession of pharmacy:
Historical background & development of pharmacy
Definition, scope of Pharmaceutics
Different dosage forms and their classification
Routes of drug administration
Factors influencing choice of dosage form
Prescription: Definition, Parts of prescription, handling of Prescription and Errors in prescription.
Posology: Definition, Factors affecting posology. Pediatric dose calculations based on age, body weight and body surface area.
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Unit 2
Pharmaceutical calculations:
- Weights and measures (metric system, apothecary system, avoirdupois system)
- Calculations involving percentage solutions, alligation, proof spirit, isotonic solutions
Powders:
- Classification of powders
- Powder properties & official preparations
- Methods of powdering & mixing
- Problems in powder formulation
- Compound powders
Liquid dosage forms: Advantages and disadvantages of liquid dosage forms. Excipients used in formulation of liquid dosage forms. Solubility enhancement techniques
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Unit 3
Monophasic liquid dosage forms:
- Solutions, syrups, elixirs, spirits, tinctures, aromatic waters
Extraction processes:
- Maceration, percolation, infusion, decoction
Evaluation of liquid preparations
Role of additives (preservatives, stabilizers, coloring, flavoring agents)
Biphasic liquids: –
Suspensions: Definition, advantages and disadvantages, classifications, Preparation of suspensions; Flocculated and Deflocculated suspension & stability problems and methods to overcome.
Emulsions: Definition, classification, emulsifying agent, test for the identification of type ofEmulsion, Methods of preparation & stability problems and methods to overcome.
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Unit 4
Suppositories: Definition, types, advantages and disadvantages, types of bases, methods of preparations. Displacement value & its calculations, evaluation of suppositories.
Pharmaceutical incompatibilities: Definition, classification, physical, chemical and therapeutic incompatibilities with examples.
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Unit 5
Semisolid dosage forms: Definitions, classification, mechanisms and factors influencing dermal penetration of drugs. Preparation of ointments, pastes, creams and gels. Excipients used in semi solid dosage forms. Evaluation of semi solid dosages forms
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