B.Pharmacy 7th Semester Novel Drug Delivery System notes covering controlled and targeted drug delivery, polymers, microencapsulation, transdermal, gastroretentive, nasopulmonary, ocular and intrauterine systems. Exam-oriented, well-structured notes for clear concepts and university exam preparation.
Novel Drug Delivery System Overview
| Bachelor of Pharmacy | |||||||
| Semester | 7th Semester | Subject | Novel Drug Delivery System | ||||
| Syllabus | |||||||
| Unit 1st | Controlled drug delivery systems: Introduction, terminology/definitions and rationale, advantages, disadvantages, selection of drug candidates.Approaches to design controlled release formulations based on diffusion, dissolution and ion exchange principles. Physicochemical and biological properties of drugs relevant to controlled release formulations Polymers: Introduction, classification, properties, advantages and application of polymers in formulation of controlled release drug delivery systems. | ||||||
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| Unit 2nd | Microencapsulation: Definition, advantages and disadvantages, microspheres/microcapsules, microparticles, methods of microencapsulation, applications Mucosal Drug Delivery system: Introduction, Principles of bioadhesion / mucoadhesion, concepts, advantages and disadvantages, transmucosal permeability and formulation considerations of buccal delivery systems Implantable Drug Delivery Systems: Introduction, advantages and disadvantages, concept of implantsand osmotic pump | ||||||
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| Unit 3rd | Transdermal Drug Delivery Systems: Introduction, Permeation through skin, factors affecting permeation, permeation enhancers, basic components of TDDS, formulation approaches Gastroretentive drug delivery systems: Introduction, advantages, disadvantages, approaches for GRDDS– Floating, high density systems, inflatable and gastro-adhesive systems and their applications Nasopulmonary drug delivery system: Introduction to Nasal and Pulmonary routes of drug delivery, Formulation of Inhalers (dry powder and metered dose), nasal sprays, nebulizers | ||||||
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| Unit 4th | Targeted drug Delivery: Concepts and approaches advantages and disadvantages, introduction to liposomes, niosomes, nanoparticles, monoclonal antibodies and their applications | ||||||
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| Unit 5th | Ocular Drug Delivery Systems: Introduction, intra ocular barriers and methods to overcome – preliminary study, ocular formulations and ocuserts Intrauterine Drug Delivery Systems: Introduction, advantages and disadvantages, development of intra uterine devices (IUDs) and applications | ||||||
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Unit Summary
Unit-I to Unit-V of the Novel Drug Delivery System course covers advanced drug delivery concepts aimed at improving therapeutic efficacy and patient compliance. Topics include controlled release systems, polymers, microencapsulation, mucosal and implantable delivery, transdermal and gastroretentive systems, nasopulmonary delivery, targeted drug delivery using liposomes and nanoparticles, and specialized systems like ocular and intrauterine drug delivery. The syllabus is concept-oriented, application-focused, and designed for strong exam preparation and practical understanding.
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